• 成功大學基礎醫學研究所博士

• 成功大學生理學研究所碩士

• 中山醫學大學醫學檢驗暨生物技術學系學士

• 遵義醫科大學珠海校區生理學教研室副教授

• 神經生理學、神經科學

• 行為神經科學、神經精神藥理學、神經電氣生理學

1. Cheng-Yuan Lai, Ming-Chun Hsieh, Dylan Chou, Kuan-Hung Lin, Hsueh-Hsiao Wang, Po-Sheng Yang, Tzer-Bin Lin ,  Hsien-Yu Peng.  The transcription factor Tbx5-dependent epigenetic modification contributes to neuropathic allodynia by activating TRPV1 expression in dorsal horn. JOURNAL OF NEUROSCIENCE. Vol.22:e0497242024. Aug. 2024. (SCI/SCIE)
2. Hui-Hsuan Lau, Cheng-Yuan Lai, Ming-Chun Hsieh, Hsien-Yu Peng, Dylan Chou, Tsung-Hsien Su, Jie-Jen Lee, Tzer-Bin Lin.  Effect of intra-vaginal electric stimulation on bladder compliance in stress urinary incontinence patients: the involvement of autonomic tone. Frontiers in Neuroscience. Vol.18:e1432616. Aug. 2024. (SCI/SCIE)
3. Zhenlong Li, Chau-Shoun Lee, Hsien-Yu Peng, Tzer-Bin Lin, Ming-Chun Hsieh, Cheng-Yuan Lai, Dylan Chou*.  Lights at night mediate depression-like behavioral and molecular phenotypes in a glucocorticoid-dependent manner in male rats. NEUROPHARMACOLOGY. Vol.248:e109888. May. 2024. (SCI/SCIE)
4. Yeh CM, Lai CY, Peng HY, Lin TB,  Chou D, Wang HH, Yang PS, Cheng JK, Peng YC, Hsieh MC.  Protein arginine methyltransferase 5 contributes to paclitaxel-induced neuropathic pain by activating transient receptor potential vanilloid 1 epigenetic modification in dorsal root ganglion. ANESTHESIA AND ANALGESIA. Vol.138(5):1107-1119. May. 2024. (SCI/SCIE)
5. Zhenlong Li, Chau-Shoun Lee, Si Chen, Benyu He , Xinya Chen, Hsien-Yu Peng, Tzer-Bin Lin, Ming-Chun Hsieh, Cheng-Yuan Lai, Dylan Chou *.  Blue light at night produces stress-evoked heightened aggression by enhancing brain-derived neurotrophic factor in the basolateral amygdala. Neurobiology of Stress. Vol.28:e100600. Jan. 2024. (SCI/SCIE)
6. Zhenlong Li, Hsien-Yu Peng, Chau-Shoun Lee, Tzer-Bin Lin, Ming-Chun Hsieh, Cheng-Yuan Lai , Han-Fang Wu , Lih-Chyang Chen, Mei-Ci Chen, Dylan Chou*.  Methylone produces antidepressant-relevant actions and prosocial effects. NEUROPHARMACOLOGY. Vol.242:e109787. Jan. 2024. (SCI/SCIE) ( SDGs3)
7. Ming-Chun Hsieh, Cheng-Yuan Lai, Li-Ting Lin, Dylan Chou, Chou-Ming Yeh , Jen-Kun Cheng , Hsueh-Hsiao Wang, Kuan-Hung Lin, Tzer-Bin Lin, Hsien-Yu Peng.  Melatonin relieves paclitaxel-induced neuropathic pain by regulating pNEK2-dependent epigenetic pathways in DRG neurons. ACS Chemical Neuroscience. Vol.14:4227-4239. Dec. 2023. (SCI/SCIE)
8. Hui-Hsuan Lau, Cheng-Yuan Lai, Ming-Chun Hsieh , Hsien-Yu Peng, Dylan Chou, Tsung-Hsien Su, Jie-Jen Lee, Tzer-Bin Lin.  Pressure-volume loop analysis of voiding workload: an application in trans-vaginal mesh-repaired pelvic organ prolapse patients. BioengineeringBioengineering-Basel. Vol.10:e853. Jul. 2023. (SCI/SCIE)
9. Li Z, Xu Y, Li R, Sheng Z, Chen X, Liu X, Lee CS, Peng HY, Lin TB, Hsieh MC, Lai CY, Wu HF, Chou D*.  BTRX-246040 acts through the ventrolateral periaqueductal gray to exert antidepressant-relevant actions in mice. International Journal of Neuropsychopharmacology. Vol.26(7):483-495. Jul. 2023. (SCI/SCIE)
10. Xu Y, Yu Z, Chen S, Li Z, Long X, Chen M, Lee CS, Peng HY, Lin TB, Hsieh MC, Lai CY, Chou D*.  (2R,6R)-hydroxynorketamine targeting the basolateral amygdala regulates fear memory. NEUROPHARMACOLOGY. Vol.225:e109402. Mar. 2023. (SCI/SCIE)
11. Wang L, Wang Y, Chen Y, Liu B, Chou D, Bian X, Li R, Wang M, Zheng C.  Rhynchophylline ameliorates cerebral ischemia by improving the synaptic plasticity in a middle cerebral artery occlusion induced stroke model. EUROPEAN JOURNAL OF PHARMACOLOGY. Vol.940:e175390. Feb. 2023. (SCI/SCIE)
12. Ye L, Xiao X, Xu Y, Zheng C, Chen S, Luo T, Li Z, Du Y, Yuan Y, Li L, Liu B, Qin W, Chou D*.  Prelimbic cortex miR-34a contributes to (2R,6R)-hydroxynorketamine-mediated antidepressant-relevant actions. NEUROPHARMACOLOGY. Vol.208:e108984. May. 2022. (SCI/SCIE)
13. Luo T, Liu H, Chen B, Liu H, Abdel-Latif A, Kitakaze M, Wang X, Wu Y, Chou D, Kim JK.  A novel role of claudin-5 in prevention of mitochondrial fission against ischemic/hypoxic stress in cardiomyocytes. Canadian Journal of Cardiology. Vol.37:1593-1606. Oct. 2021. (SCI/SCIE)
14. Chou D*.  Topiramate inhibits offensive aggression through targeting ventrolateral periaqueductal gray. NEUROPHARMACOLOGY. Vol.181:e108361. Dec. 2020. (SCI/SCIE)
15. Chou D.  Brain-derived neurotrophic factor in the ventrolateral periaqueductal gray contributes to (2R,6R)-hydroxynorketamine-mediated actions. NEUROPHARMACOLOGY. Vol.170:e108068. Jun. 2020. (SCI/SCIE)
16. Ko CY, Yang YB, Chou D, Xu JH.  The ventrolateral periaqueductal gray contributes to depressive-like behaviors in recovery of inflammatory bowel disease rat model. Frontiers in Neuroscience. Vol.14:e254. Mar. 2020. (SCI/SCIE)
17. Liu Q, Ko CY, Zheng C, Ye L, Liu B, Gao H, Huang D, Chou D*.  Decreased glutamatergic synaptic strength in the periaqueductal gray contributes to maintenance of visceral pain in male rats with experimental pancreatitis. NEUROSCIENCE. Vol.428:60-69. Jan. 2020. (SCI/SCIE)
18. Ko CY, Hu AK, Chou D, Huang LM, Su HZ, Yan FR, Zhang XB, Zhang HP, Zeng YM.  Analysis of oral microbiota in patients with obstructive sleep apnea-associated hypertension. HYPERTENSION RESEARCH. Vol.42-No.11:1692-1700. Nov. 2019. (SCI/SCIE)
19. Ye L, Ko CY, Huang Y, Zheng C, Zheng Y, Chou D*.  Ketamine metabolite (2R,6R)-hydroxynorketamine enhances aggression via periaqueductal gray glutamatergic transmission. NEUROPHARMACOLOGY. Vol.157:e107667. Oct. 2019. (SCI/SCIE)
20. Ko CY, Liu QQ, Su HZ, Zhang HP, Fan JM, Yang JH, Hu AK, Liu YQ, Chou D*, Zeng YM.  Gut microbiota in obstructive sleep apnea-hypopnea syndrome: disease-related dysbiosis and metabolic comorbidities. Clinical Science. Vol.133-No.7:905-917. Apr. 2019. (SCI/SCIE)
21. Lai CY, Hsieh MC, Ho YC, Wang HH, Chou D, Wen YC, Yang PS, Cheng JK, Peng HY.  Spinal RNF20-mediated histone H2B monoubiquitylation regulates mGluR5 transcription for neuropathic allodynia. JOURNAL OF NEUROSCIENCE. Vol.38-No.43:9160-9174. Oct. 2018. (SCI/SCIE)
22. Chou D, Peng HY, Lin TB, Lai CY, Hsieh MC, Wen YC, Lee AS, Wang HH, Yang PS, Chen GD, Ho YC.  (2R,6R)-hydroxynorketamine rescues chronic stress-induced depression-like behavior through its actions in the midbrain periaqueductal gray. NEUROPHARMACOLOGY. Vol.139:1-12. Sep. 2018. (SCI/SCIE)
23. Hsieh MC, Ho YC, Lai CY, Chou D, Chen GD, Lin TB, Peng HY.  Spinal TNF-α impedes Fbxo45-dependent Munc13-1 ubiquitination to mediate neuropathic allodynia in rats. Cell Death & Disease. Vol.9-No.8:e811. Jul. 2018. (SCI/SCIE)
24. Lai CY, Hsieh MC, Ho YC, Chen GD, Chou D, Ruan T, Lee AS, Wang HH, Chau YP, Peng HY, Lai CH.  GluN2B/CaMKII mediates CFA-induced hyperalgesia via HDAC4-modified spinal COX2 transcription. NEUROPHARMACOLOGY. Vol.135:536-546. Jun. 2018. (SCI/SCIE)
25. Ho YC, Lin TB, Hsieh MC, Lai CY, Chou D, Chau YP, Chen GD, Peng HY.  Periaqueductal gray glutamatergic transmission governs chronic stress-induced depression. NEUROPSYCHOPHARMACOLOGY. Vol.43-No.2:302-312. Jan. 2018. (SCI/SCIE)
26. Hsieh MC, Ho YC, Lai CY, Chou D, Wang HH, Chen GD, Lin TB, Peng HY.  Melatonin impedes Tet1-dependent mGluR5 promoter demethylation to relieve pain. JOURNAL OF PINEAL RESEARCH. Vol.63-No.4:e12436. Nov. 2017. (SCI/SCIE)
27. Chiou CS, Chen CC, Tsai TC, Huang CC, Chou D, Hsu KS.  Alleviating bone cancer-induced mechanical hypersensitivity by inhibiting neuronal activity in the anterior cingulated cortex. ANESTHESIOLOGY. Vol.125-No.4:779-792. Oct. 2016. (SCI/SCIE)
28. Huang CC, Chou D, Yeh CM, Hsu KS.  Acute food deprivation enhances fear extinction but inhibits long-term depression in lateral amygdala via ghrelin signaling. NEUROPHARMACOLOGY. Vol.101:36-45. Feb. 2016. (SCI/SCIE)
29. Chou D, Huang CC, Hsu KS.  Brain-derived neurotrophic factor in the amygdala mediates susceptibility to fear conditioning. EXPERIMENTAL NEUROLOGY. Vol.255:19-29. May. 2014. (SCI/SCIE)
30. Peng HY, Chang HM,  Chang SY, Tung KC, Lee SD, Chou D, Lai CY, Chiu CH, Chen GD, Lin TB.  Orexin-A modulates glutamatergic NMDA-dependent spinal reflex potentiation via inhibition of NR2B subunit. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM. Vol.295-No.1:E117-129. Jul. 2008. (SCI/SCIE)
31. Peng HY, Cheng YW, Lee SD, Ho YC, Chou D, Chen GD, Cheng CL, Hsu TH, Tung KC, Lin TB.  Glutamate-mediated spinal reflex potentiation involves ERK 1/2 phosphorylation in anesthetized rats. NEUROPHARMACOLOGY. Vol.54-No.4:686-698. Mar. 2008. (SCI/SCIE)

dylanchou@mmc.edu.tw