趙巧瑄
職稱 助理教授
主要學歷

國立成功大學 基礎醫學研究所博士

長庚大學 醫學生物技術暨檢驗學系學士

主要經歷

國立成功大學 博士後研究員

猶他大學 訪問學者

教學專長

臨床病毒學、臨床血清免疫學、免疫學、臨床血液學

研究專長

病毒學 (登革病毒、新型冠狀病毒)

免疫學 (先天性免疫、抗體學、疫苗學、臨床血清免疫學)

檢驗醫學 (病毒分子流行病學、生物標記物分析、實驗室自行研發檢驗技術(LDTs)開發)

血液學 (血小板、嗜中性球、血管內皮細胞)

學術期刊
  1. Cheng YL, Chang SS, Chao CH, Chen PT, Lin YL, Syu GD, Lee NY, Chen PL, Lo WC, Ho TS.  Optimizing SARS-CoV-2 vaccine responses in kidney transplant recipients: an urgent need. Microbiology Spectrum. Vol.12-No.6:e00004-24. May. 2024. (SCI/SCIE)
  2. Hsieh KH, Chao CH, Cheng YL, Lai YC, Chuang YC, Wang JR, Chang SY, Hung YP, Chen YM, Liu WL, Chuang WJ, Yeh TM.  Enhancement of NETosis by ACE2-cross-reactive anti-SARS-CoV-2 RBD antibodies in patients with COVID-19. JOURNAL OF BIOMEDICAL SCIENCE. Vol.31-No.1:39-39. Mar. 2024. (SCI/SCIE)
  3. Hsieh WS, Chao CH, Shen CY, Cheng D, Huang SW, Wang YF, Chen CC, Chen SH, Hsu LJ, Wang JR.  VP1 codon deoptimization and high-fidelity substitutions in 3D polymerase as potential vaccine strategies for eliciting immune responses against enterovirus A71. Journal of Virology. Vol.98-No.1:e0155823.. Jan. 2024. (SCI/SCIE)
  4. Ling TC, Chen PL, Li NY, Ko WC, Sun CY, Chao JY, Shieh CC, Shen CF, Wu JL, Huang TC, Chao CH, Wang JR.  Trajectory of Humoral Responses to Two Doses of ChAdOx1 nCoV-19 Vaccination in Patients Receiving Maintenance Hemodialysis. Microbiology Spectrum. Vol.11-No.2:e0344522. Feb. 2023. (SCI/SCIE)
  5. Chao CH, Cheng D, Huang SW, Chuang YC, Yeh TM, Wang JR.  Serological responses triggered by different SARS-CoV-2 vaccines against SARS-CoV-2 variants in Taiwan. Frontiers in Immunology. Vol.13:e1023943. Oct. 2022. (SCI/SCIE)
  6. Cheng YL, Chao CH, Lai YC, Hsieh KH, Wang JR, Wan SW, Huang HJ, Chuang YC, Chuang WJ, Yeh TM.  Antibodies against the SARS-CoV-2 S1-RBD cross-react with dengue virus and hinder dengue pathogenesis. Frontiers in Immunology. Vol.13:e941923. Jul. 2022. (SCI/SCIE)
  7. Lai YC, Cheng YW, Chao CH, Chang YY, Chen CD, Tsai WJ, Lin YS, Chang CP, Chuang WJ, Chen YL, Wang YR, Chang SY, Huang W, Wang JR, Tseng CK, Lin CK, Chuang YC, Yeh TM.  Antigenic Cross-Reactivity Between SARS-CoV-2 S1-RBD and Its Receptor ACE2. Frontiers in Immunology. Vol.13:e868724. Apr. 2022. (SCI/SCIE)
  8. Lai YC, Chao CH, Yeh TM.  Roles of Macrophage Migration Inhibitory Factor in Dengue Pathogenesis: From Pathogenic Factor to Therapeutic Target. Microorganisms. Vol.8-No.6:891-891. Jun. 2020. (SCI/SCIE)
  9. Huang HJ, Yang M, Chen HW, Wang S, Chang CP, Ho TS, Kao YS, Tien SM, Lin HH, Chang PC, Lai YC, Hsiao YP, Liu YL, Chao CH, Anderson R, Yeh TM, Lin YS, Wan SW.  A novel chimeric dengue vaccine candidate composed of consensus envelope protein domain III fused to C-terminal-modified NS1 protein. VACCINE. Vol.40:2299-2310. Apr. 2020. (SCI/SCIE)
  10. Chao CH, Wu WC, Lai YC, Tsai PJ, Perng GC, Lin YS, Yeh TM.  Dengue virus nonstructural protein 1 activates platelets via Toll-like receptor 4, leading to thrombocytopenia and hemorrhage. PLoS Pathogens. Vol.15-No.4:e1007625. Feb. 2019. (SCI/SCIE)
  11. Lu LH, Chao CH, Yeh TM.  Inhibition of autophagy protects against sepsis by concurrently attenuating the cytokine storm and vascular leakage. JOURNAL OF INFECTION. Vol.78-No.3:178-186. Dec. 2018. (SCI/SCIE)
  12. Chao CH, Chen HR, Chuang YC, Yeh TM.  Macrophage migration inhibitory factor-induced autophagy contributes to thrombin-triggered endothelial hyperpermeability in sepsis. Shock. Vol.50-No.1:103-111. Jul. 2018. (SCI/SCIE)
  13. Chen HR, Chao CH, Liu CC, Ho TS, Tsai HP, Perng GC, Lin YS, Wang JR, Yeh TM.  Macrophage migration inhibitory factor is critical for dengue NS1-induced endothelial glycocalyx degradation and hyperpermeability. PLoS Pathogens. Vol.14-No.4:e1007033. Apr. 2018. (SCI/SCIE)
計畫
計畫起訖年月計畫名稱擔任職務
2024-02~2027-01新聘教師研究室設置補助(A)_MMC-RD-112-2A-P002_趙巧瑄主持人
電子郵件

chaoch@mmc.edu.tw

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